การทดสอบรอยรั่วซึมด้วยฮีเลียม Helium Technology Leak Detection

การทดสอบรอยรั่วซึมด้วยฮีเลียม เราอาจจะไม่ค่อยได้ยินชื่อฮีเลียมในการทดสอบรอยรั่วซึมโดยทั่วไป แต่ในอุตสาหกรรมยาและการแพทย์ helium ถูกนำมาใช้ในการตรวจสอบรอยรั่วซึมขนาดเล็ก micro-leak ด้วยคุณสมบัติของมัน ที่จะวิ่งไปหารอยรั่วขนาดเล็ก โดยธรรมชาติเราจึงนำคุณสมบัตินี้มาใช้ในการตรวจจับรอยรั่วขนาดเล็กได้เป็นอย่างดี

Helium leak testing is defined as the act of finding leaks in different types of enclosed or sealed systems using helium as a “tracer” gas and its concentration is measured as it escapes due to leakage. A vial, consisting of a container and elastomeric closure, is a good example of a package system. A vial is helium-filled & is subjected to vacuum. The amount of helium escaping that package is quantitatively measured and stated as a leak rate. Other examples include a prefilled syringe, a foil pouch or a cold form blister card. Each of these package types is designed and intended to keep the drug product contained while keeping out any detrimental environmental contaminants, such as debris, microorganisms, or even gases. The helium leak detection method has the sensitivity to evaluate each of them.

Helium Leak Detection Technology

Helium gas has certain key qualities that make it ideal for package leak testing:

Helium gas is one of the smallest molecules, allowing it to breach pathways reliably and quickly. It is an inert gas & it will not interact with the components being tested, thus making it is safe to use. The instrument noise due to environmental helium is inherently low because of its limited presence in the atmosphere at less than 5ppm and thus gives incredibly accurate reports.